| Unit name | Gene expression and rearrangement |
|---|---|
| Unit code | MOLG22200 |
| Credit points | 20 |
| Level of study | I/5 |
| Teaching block(s) |
Teaching Block 2 (weeks 13 - 24) |
| Unit director | Dr. Brown |
| Open unit status | Not open |
| Pre-requisites |
None |
| Co-requisites |
None |
| School/department | School of Biochemistry |
| Faculty | Faculty of Life Sciences |
This unit covers the processes involved in maintaining and expressing the genetic material of microorganisms, plants and animals, as well as the molecular genetic basis of a number of important disease states, and the use of molecular techniques for the detection and treatment of genetic diseases. Topics covered include: DNA-protein interactions; mechanisms of DNA replication, recombination and repair; eukaryotic and prokaryotic gene expression; protein synthesis; generation of immune diversity by rearrangement of immunoglobulin genes; molecular genetics of disease (e.g. cancer and AIDS); plant molecular genetics; medical molecular genetics. 35 lectures are supplemented with five practical sessions and three tutorials. Assessment is by sessional examination (80%), a multiple choice examination (5%), assessed exercises associated with the tutorials (10%) and laboratory reports (5%). Some prior knowledge of molecular biology (eg equivalent to Biochemistry 1G) is recommended.
