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| Unit name |
The Application of Transfusion and Transplantation Sciences (TTS-B) |
| Unit code |
PANMM0009 |
| Credit points |
40 |
| Level of study |
M/7
|
| Teaching block(s) |
Teaching Block 4 (weeks 1-24)
|
| Unit director |
Dr. Nicola Anderson |
| Open unit status |
Not open |
| Pre-requisites |
None |
| Co-requisites |
None |
| School/department |
School of Cellular and Molecular Medicine |
| Faculty |
Faculty of Life Sciences |
Description including Unit Aims
The TTS-B unit provides lectures on applied aspects of transfusion and transplantation. Within Bristol there is a large blood processing centre, the UK transplant service, a kidney transplant unit, an eye bank, a heart valve bank and a pancreatic cell transplant research unit. NHSBT also bank several tissues at other centres. Students therefore have a unique opportunity to meet some of the country's leading authorities in diverse fields of transplantation. This core unit will provide the essential knowledge needed to apply the basis science to contemporary clinical and laboratory practice both for service and research. The unit comprises approximately 60 hours of lectures, tutorials and two assignments. The unit is taught in modules comprising: Blood donation, blood components and plasma products, donation testing, tissue banking and engineering, stem cell transplants, solid organ transplants and hospital transfusion.
Aims:
- Principles underlying this module such as quality systems, codes of good practice, risk assessment, and informed consent
- To teach the principles of blood, tissue and cell collection processes, their specialised manipulations for clinical use, testing and storage
- To explain donor selection and testing, organ allocation and complications of transfusion and transplantation.
- Appropriate indications/protocols for blood components and products including those for specialised patient groups
- Serological investigations of red cell antibodies including antenatal samples
- Indications and use of organ, tissue and stem cell transplantation
- To evaluate topics such as complications of transfusion and transplantation, their scientific principles, treatment and avoidance.
- To discuss ethical issues of transfusion and transplantation
- To introduce discussion of cost, health benefit and feasibility of “safe blood or transplantation”
- To provide opportunities for use of library and computer aided learning and internet educational tools through assignments and tutorials
- To develop a high level writing and appraisal skills through assignments which reflect or assist the role of the student in their future workplace.
Intended Learning Outcomes
Upon completion of the unit, the student should be able to demonstrate or be able to:
- A broad and in depth understanding of blood, tissue and cell collection processes, their specialised manipulations for clinical use, testing and storage.
- A broad and in depth understanding of donor selection and testing, organ allocation and complications of transfusion and transplantation.
- An in depth understanding of patient testing, use blood components and products
- Deal with complex issues systematically and creatively. For example by considering the introduction of a new test and the involvement of a multidisciplinary team.
- Show decision making in complex and unpredictable situations. For example in the investigation of an antibody to a high frequency antigen.
- Students should be able to evaluate new methodologies for example in donor testing and develop critiques of them.
- Show a critical awareness of current problems such as vCJD.
- Critically evaluate current research in the discipline.
- Show originality in the discussion and synthesis of information.
- Demonstrate independent learning ability following lectures and tutorials.
- Communicate with specialist and non specialist audiences (eg general public, colleagues, other scientists) using written and verbal skills.
- Demonstrate Use the library, computer-aided learning, the internet and other research and educational tools
The above are assessed as follows:
Short exam questions; 1, 2, 3
Exam essay questions; 1, 2, 3, 4, 6, 7, 9, 10
Assignments 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
Teaching Information
Lectures and tutorials
Assessment Information
Two 2500 word assignments and an exam.
The exam has two parts. Part 1 consists of 20 MCQs or short answer questions. All questions are compulsory. Part 2 consists of three essay questions answered from a choice of six. The whole exam lasts three hours
Reading and References
Practical Transfusion Medicine. Ed Murphy & Pamphilon
Handbook of Transfusion Medicine. D B L McClelland (Editor). TSO
Postgraduate haematology A. V. Hoffbrand, S.M Lewis and E. G.D. Tuddenham (2001) Arnold
Primer on Transplantation. D J Norman. L A Turka. Edition 2 2001. Blackwell
