Unit information: Neurodegeneration and Ophthalmic Disorders in 2024/25

Unit name Neurodegeneration and Ophthalmic Disorders
Unit code CSSBM1012
Credit points 20
Level of study M/7
Teaching block(s) Teaching Block 1 (weeks 1 - 12)
Unit director Dr. Cordero Llana
Open unit status Not open
Units you must take before you take this one (pre-requisite units)

None

Units you must take alongside this one (co-requisite units)

None

Units you may not take alongside this one

none

School/department Bristol Medical School
Faculty Faculty of Health Sciences

Unit Information

Why is this unit important?

Neurodegenerative and ophthalmic disorders are becoming more prevalent in an ageing world where life expectancy is progressively increasing. These conditions have a profound impact in the life of those affected. There is currently no cure for any of these conditions and we can only offer symptomatic treatments for those affected. Stem Cells and Regenerative medicine have started to offer alternative and potential effective approaches to tackle these conditions.

How does this unit fit into your programme of study

Throughout the programme you will gain an understanding of regenerative medicine approaches, biomaterials and molecular tools that can be used to address unmet clinical needs. In this unit we will apply this foundational knowledge in the context of CNS repair aiming to tackle common neurodegenerative and ophthalmic disorders.

Your learning on this unit

An overview of content

The aim of this unit is to introduce you to neurodegenerative disorders and how stem cells & regenerative medicine approaches are being developed to tackle these conditions. We will take you through basic CNS biology, the generation of specific neural populations and the pathophysiological mechanisms that play a role in neurodegeneration. Examples and case studies will cover both pre-clinical and clinical applications.

How will students, personally, be different as a result of the unit

As a result of this unit, you will gain further experience in expressing your own views of scientific research, critically evaluating publications, and identifying where gaps in the field still exist. You will start to explore different communication methods commonly used by scientists to share their findings.

Learning Outcomes

  1. Gain a thorough understanding of the pathophysiology and symptomatology of common neurodegenerative disorders and how this can be targeted using regenerative medicine approaches.
  2. Appraise current pre-clinical and clinical stem cell and regenerative therapies for CNS repair.
  3. Be able to critically analyse data and present findings illustrating different ways of communicating scientific information.

How you will learn

This unit will offer you a range of learning opportunities such as pre-recorded resources together with live online sessions with discussion designed to encourage engagement and active learning. Formative tasks will encourage you to develop your skills and support your learning. You are also expected to engage in selecting additional reading from a suggested reading list, to support and further expand your learning.

How you will be assessed

Tasks which help you learn and prepare you for summative tasks (formative):

  • Formative feedback during the poster production assessment.
  • A live discussion session will provide opportunity for you to discuss your ideas on structure and content of the summative essay.

Tasks which count towards your unit mark (summative):

  • 1 scientific poster contributing 45% to the final unit mark (ILO 1-3)
  • 1x essay contributing 55% to the final unit mark (ILO 1-3)

When assessment does not go to plan

If you do not pass the unit, you will normally be given the opportunity to take a reassessment as per the Regulations and Code of Practice for Taught Programmes. Decisions on the award of reassessment will normally be taken after all taught units of the year have been completed. Reassessment will normally be in a similar format to the original assessment that has been failed.

Resources

If this unit has a Resource List, you will normally find a link to it in the Blackboard area for the unit. Sometimes there will be a separate link for each weekly topic.

If you are unable to access a list through Blackboard, you can also find it via the Resource Lists homepage. Search for the list by the unit name or code (e.g. CSSBM1012).

How much time the unit requires
Each credit equates to 10 hours of total student input. For example a 20 credit unit will take you 200 hours of study to complete. Your total learning time is made up of contact time, directed learning tasks, independent learning and assessment activity.

See the University Workload statement relating to this unit for more information.

Assessment
The assessment methods listed in this unit specification are designed to enable students to demonstrate the named learning outcomes (LOs). Where a disability prevents a student from undertaking a specific method of assessment, schools will make reasonable adjustments to support a student to demonstrate the LO by an alternative method or with additional resources.

The Board of Examiners will consider all cases where students have failed or not completed the assessments required for credit. The Board considers each student's outcomes across all the units which contribute to each year's programme of study. For appropriate assessments, if you have self-certificated your absence, you will normally be required to complete it the next time it runs (for assessments at the end of TB1 and TB2 this is usually in the next re-assessment period).
The Board of Examiners will take into account any exceptional circumstances and operates within the Regulations and Code of Practice for Taught Programmes.