Unit information: Powering Biomolecular Interactions in 2025/26

Please note: Programme and unit information may change as the relevant academic field develops. We may also make changes to the structure of programmes and assessments to improve the student experience.

Unit name Powering Biomolecular Interactions
Unit code BIOC10010
Credit points 20
Level of study C/4
Teaching block(s) Teaching Block 2 (weeks 13 - 24)
Unit director Dr. Baker
Open unit status Not open
Units you must take before you take this one (pre-requisite units)

A-level Chemistry or equivalent strongly advised.

Units you must take alongside this one (co-requisite units)

BIOC10007 – Fundamental Skills for Biochemists

Units you may not take alongside this one

None

School/department School of Biochemistry
Faculty Faculty of Life Sciences

Unit Information

Deputy Unit Director: Professor Mike Jones

Why is this unit important?

The overall aim of this unit is to provide coverage of key concepts that underlie the dynamics of biomolecules and their interactions. This includes the binding of ligands and enzyme catalysis, and the role of energy in driving biomolecular interactions. The unit examines the variety of forms in which energy can be stored and utilised in biological systems, from both conceptual and mathematical viewpoints.

How does this unit fit into your programme of study?

This unit provides a basic grounding in the chemical and physical concepts that are key to an understanding of how biomolecules interact in living systems, and the mechanisms and structures underpinning energy capture, conversion, storage and utilisation. Unit content complements material covered in BIOC10009 Biochemistry: Cellular Processes (Honours), deepening understanding of the chemistry of biomolecular interaction and interconversion to a level commensurate with a degree in Biochemistry.

Your learning on this unit

An overview of content

Topics covered in this unit include:

  • Thermodynamics basics
  • Ligand binding
  • Reaction kinetics
  • Free energy in biological systems
  • Energy from ATP
  • Energy from electrons
  • Energy from gradients
  • Energy from the sun
  • Metals in biology

How will students, personally, be different as a result of the unit?

At the end of the unit a successful student will be able to demonstrate:

  1. An understanding of basic thermodynamic principles.
  2. An understanding of how proteins interact with small molecule ligands.
  3. An understanding of the kinetics of biomolecular reactions including enzyme catalysis.
  4. An appreciation for the different forms and roles of energy in driving biomolecular interactions.
  5. Knowledge of how biomolecular interactions are driven by redox, photosynthetic, proton gradient and thermodynamic processes;
  6. Proficiency in the use of basic mathematical operations used in the analysis of biomolecular interactions.
  7. Appreciation of the roles metals play in biochemical systems and reactions.
  8. An understanding of basic biochemical analyses and the use of simple laboratory apparatus;
  9. An ability to comprehend, communicate and explain scientific knowledge and research methods within the field of biomolecular research at an elementary level in writing.

Learning Outcomes

Learning on this unit directly addresses components of the Bristol Skills Profile, including:

  • How to develop effective learning strategies.
  • How to think critically.
  • How to analyse and present data.
  • Work well as part of a team.
  • Able to identify and work with technological advances.

How you will learn

The teaching in the unit is normally delivered through a combination of synchronous and asynchronous activities including lectures, workshops and laboratory classes.

How you will be assessed

Tasks which help you learn and prepare you for summative tasks (formative):

The unit is normally supported by formative workshops that build ability and confidence in the analytical and numerical skills required by scientists. The unit is supported by online resources delivered through Blackboard and eBiolabs that include formative tests and other opportunities to test understanding.

Tasks which count towards your unit mark (summative):

The components that make up the unit assessment are:

  • Ligand Binding Coursework: 20%
  • News and Views Coursework: 20%
  • End of unit exam: 60%

To earn credit for this unit you must normally have made a reasonable attempt at each of the components of the unit assessment. A reasonable attempt requires a student to have undertaken the assessment activity and engaged with its purpose in the academic judgement of the relevant Unit Director, or nominee.

Marks earned for laboratory classes count towards the unit mark for co-requisite unit BIOC10007 – Fundamental Skills for Biochemists.

When assessment does not go to plan

For all components, reassessment normally involves a second attempt at the same form of assessment.

Resources

If this unit has a Resource List, you will normally find a link to it in the Blackboard area for the unit. Sometimes there will be a separate link for each weekly topic.

If you are unable to access a list through Blackboard, you can also find it via the Resource Lists homepage. Search for the list by the unit name or code (e.g. BIOC10010).

How much time the unit requires
Each credit equates to 10 hours of total student input. For example a 20 credit unit will take you 200 hours of study to complete. Your total learning time is made up of contact time, directed learning tasks, independent learning and assessment activity.

See the University Workload statement relating to this unit for more information.

Assessment
The assessment methods listed in this unit specification are designed to enable students to demonstrate the named learning outcomes (LOs). Where a disability prevents a student from undertaking a specific method of assessment, schools will make reasonable adjustments to support a student to demonstrate the LO by an alternative method or with additional resources.

The Board of Examiners will consider all cases where students have failed or not completed the assessments required for credit. The Board considers each student's outcomes across all the units which contribute to each year's programme of study. For appropriate assessments, if you have self-certificated your absence, you will normally be required to complete it the next time it runs (for assessments at the end of TB1 and TB2 this is usually in the next re-assessment period).
The Board of Examiners will take into account any exceptional circumstances and operates within the Regulations and Code of Practice for Taught Programmes.